Alison Woodcock, M Charlton and Clare Bradley (2007)
Extent of satisfaction with tablets and food-timing in sulphonylurea-treated diabetes. Diabetes Research and Clinical Practice, 78 (3).
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This study measured patient views about following tablet-taking and food-timing recommendations in Type 2 diabetes. Two new questionnaires were validated. Outpatients with Type 2 diabetes treated with sulphonylurea agents (n = 131) completed the seven-item Diabetes Tablet Treatment Questionnaire (DTTQ) and nine-item Diabetes Food Timing Questionnaire (DFTQ). Mean glycosylated haemoglobin (HbA1c) was 7.8% (S.D. 1.8%). At least 74% had optimal DTTQ item scores for tablet-taking as recommended, difficulty taking tablets, side effects, perceived hypoglycaemia and willingness to continue current tablets, but 71% scored sub-optimally regarding recent hyperglycaemia. Under half scored optimally on DFTQ items concerning eating at recommended times, difficulty with food-timing, denying oneself food and guilt about eating. Principal components and reliability analyses identified a two-item tablet problem scale within the DTTQ (α 0.72) and a seven-item food-timing problem scale in the DFTQ (α 0.77). Satisfaction and adherence were not closely related to glycaemic control. Only scores for perceived hyperglycaemia (r = 0.38), perceived hypoglycaemia (r = −0.24) and satisfaction to continue current tablets (r = −0.20) correlated significantly with HbA1c. Clinicians found that the DTTQ helped to raise tablet-taking issues otherwise missed in consultations. Both questionnaires can be used to guide the need for focussed discussion, educational intervention and/or treatment change and to evaluate their impact
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The study was funded by a research grant from Aventis Pharma.
 British Medical Association and Royal Pharmaceutical Society of Great Britain, British National Formulary 45, March 2003, British Medical Association and Royal Pharmaceutical Society of Great Britain, London, 2003, pp. 335–339.
 UK Prospective Diabetes Study Group, Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33), The Lancet 352 (1998), pp. 837–853.
 B.S. Bloom, Daily regimen and compliance with treatment: fewer daily doses and drugs with fewer side effects improve compliance, Br. Med. J. 323 (2001), p. 647. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (39)
 R. Gadsby and M. MacKinnon, Steps to better compliance in diabetic patients, Practitioner 243 (February (1595)) (1999), p. 103 106, 108. View Record in Scopus | Cited By in Scopus (1)
 C. Bradley and K.S. Lewis, Measures of psychological well-being and treatment satisfaction developed from the responses of people with tablet-treated diabetes, Diab. Med. 7 (1990), pp. 445–451. View Record in Scopus | Cited By in Scopus (100)
 C. Bradley, The Diabetes Treatment Satisfaction Questionnaire (DTSQ). In: C. Bradley, Editor, Handbook of Psychology and Diabetes: A Guide to Psychological Measurement in Diabetes Research and Practice, Harwood Academic, Chur, Switzerland (1994), pp. 111–132.
 C. Bradley and J. Speight, Patient perceptions of diabetes and diabetes therapy: assessing quality of life, Diab. Metab. Res. Rev. 18 (2002), pp. S64–S69. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (41)
 C. Bradley, C. Todd, T. Gorton, L. Symonds, A. Martin and R. Plowright, The development of an individualised questionnaire measure of perceived impact of diabetes on quality of life: the ADDQoL, Qual. Life Res. 8 (1999), pp. 79–91. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (74)
 A.J. Woodcock, S. Julious, A.L. Kinmonth and M.J. Campbell, Problems with performance of the SF-36 amongst people with Type 2 diabetes in general practice, Qual. Life Res. 10 (2001), pp. 661–670. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (23)
 DAFNE Study Group, Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial, Br. Med. J. 325 (2002), pp. 746–749.
 Diabetes UK, Eating well: eight steps to healthy eating. http://www.diabetes.org.uk/eatwell/meal_planning/eightsteps.htm, 2003 (accessed 7 September 2004).
 M.J. Franz, J.P. Bantle, C.A. Beebe, J.D. Brunzell, J.L. Chiasson and A. Garg et al., American Diabetes Association, Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications, Diab. Care 25 (2002), pp. 148–198. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (170)
 The Diabetes Care and Complications Trial Research Group, The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus, N. Engl. J. Med. 329 (1993), pp. 977–986.
 S. Manley, W.G. John and S. Marshall, Introduction of IFCC reference method for calibration of HbA1c: implications for clinical care, Diab. Med. 21 (2004), pp. 673–676. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (12)
 A.J. Woodcock and C. Bradley, Validation of the HIV Treatment Satisfaction Questionnaire, Qual. Life Res. 10 (2001), pp. 517–531. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (18)
 K.M. Loewenthal, An Introduction to Psychological Tests and Scales, UCL Press Limited, London (1996).
 R. Plowright, E. Witthaus and C. Bradley, Psychometric evaluation of Diabetes Treatment Satisfaction Questionnaire in eight languages, Proc. Br. Psych. Soc. 8 (2000), p. 43.