Bowes, J. H. (1936)
The chemical composition of teeth. Chemical composition in relation to dental structure.
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The main object of this work is to determine the chemical composition of teeth of good structure and of varying degrees of hypoplasia, in order that the question of the relationship between chemical composition and hypoplasia may be considered. The term hypoplasia is here used in the sense intended by Mellanby (1923-34), who has already established a relation between the histological structure and the hypoplasia exhibited, with the susceptibility to dental caries. The chemical composition of teeth appears to have aroused little interest until the end of the nineteenth century, when analyses were made by Berzelius, followed by Hoppe-Seyler, Von Bibra and others. These workers all agree that calcium and phosphorus are the main constituents of teeth and bone, but apart from this their analyses differ considerably. The greater part of the work since 1900 has been concentrated on two problems: the nature of the calcium compound and the amount of organic substance present. The general opinion was that the calcium occurred chiefly in combination with the phosphorus. As early as 1862, Hoppe-Seyler noticed that the calcium and phosphorus ratio in bones and teeth corresponded very nearly with that for apatite.
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Institution: University of London, Royal Holloway and Bedford New College (United Kingdom).